Job Description
The Paradromics Neuroscience team is seeking a highly motivated and experienced Neuroscientist to advance the preclinical testing of our Connexus® Direct Data Interface (DDI) and drive translational R&D experiments utilizing the DDI system in large animal models. This position offers an exciting opportunity to contribute to the development of next-generation brain implants designed to address serious physical and mental health conditions.
We are seeking a proactive, self-starter with a "can-do" attitude who thrives in a dynamic and collaborative environment. You should be resourceful, adaptable, and motivated by intellectual challenges. You should be resilient and tenacious to provide high-quality deliverables under tight timelines. Exceptional communication and interpersonal skills are essential, as this role involves close teamwork across multidisciplinary teams.
This on-site position in Austin, Texas, is part of the Paradromics Science team, which includes Neuroscience and Data Science & Engineering. If you’re eager to apply your skills in a meaningful and impactful way, enjoy intellectual challenges, and value working alongside passionate and dedicated colleagues, this role will be highly rewarding and fulfilling.
Key Responsibilities
- Owning the in vivo electrophysiology experimental pipeline, encompassing experiment conceptualization/design/execution, experimental instrumentation development, and neurophysiology data analysis. These efforts support Paradromics validation and verification testing, as well as forward-looking preclinical R&D initiatives.
- Collaborating with Neuroscience, Data Science & Engineering, and Clinical team members to advance, optimize, and test offline and online neural signal processing pipelines.
- Collaborating with the Electrical Engineering Team to refine signal chain design specifications.
- Supporting the Hardware Engineering Team to refine design specifications for neural implants and surgical instruments.
- Staying abreast of the latest developments in BCI and Neuromodulation research to inform system design, technology development, and biomarker discovery.
- Working closely with Regulatory Affairs, Quality Assurance, Project Management, Operations, and external CROs to ensure alignment and compliance with regulatory and quality standards.
- Contributing to the preparation of manuscripts, presentations, and other technical, scientific, regulatory, and marketing materials.
Required Skills & Experience
- Deep expertise in designing, setting up, and executing electrophysiology experiments in chronic, awake animal models, incorporating sensorimotor and/or cognitive tasks and synchronized neural and behavioral data acquisition.
- Proficiency in working with electrophysiology data (e.g., spiking activity, field potentials) and behavioral data related to sensorimotor and/or cognitive processes.
- Experience in analyzing and visualizing large-scale time series data.
- Fluency in Python with hands-on experience using scientific computing and machine learning libraries such as NumPy, Pandas, SciPy, Scikit-learn, and PyTorch.
- Comfortable working in a Linux environment and familiar with git and github, gitlab, or similar.
- Ability to develop clear, detailed standard operating procedures and technical reports.
- Ability to contribute to presentations and create technical/scientific content for regulatory submissions, scientific presentations, and peer-reviewed manuscripts.
- Ability to work independently and as part of a team, and have excellent communication and interpersonal skills.
- Willingness and ability to travel up to 30% for preclinical surgical procedures and experiments.
Preferred Skills & Experience
- Experience in planning, preparing, and conducting cranial implantation surgeries (e.g., craniotomy, durotomy, implantation of electrode, optical fibers, or optical lens) ideally in large animal models such as non-human primates, ovine, and swine.
- Experience in developing algorithms for decoding and modulating large-scale neural population and dynamics, with a focus on data from intracranial implants.
- Experience in applying signal processing and/or machine learning techniques to electrophysiology data for decoding, tracking, and manipulating neural dynamics and brain states, particularly in the context of neuromodulation systems (e.g., optical, electrical, magnetic, pharmaceutical, or ultrasonic) in preclinical or clinical BCI studies.
- Proven track record of publishing impactful, well-cited research in high-impact scientific journals.
- Knowledge of neuromodulation and bioelectronic devices in the nervous system.
- Experience in the medical device industry or other highly regulated environment.
- Experience conducting GLP animal studies intended for submission to the FDA or other regulators.
Required Education
- Ph.D. in Neuroscience, Bioengineering/Biomedical Engineering, Electrical Engineering, or other hard Science and Engineering disciplines with thesis work or postdoctoral work relevant to systems neuroscience, neural engineering or equivalent experience through industry roles.
Paradromics is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, or national origin.
